Description
Allograft inflammatory factor 1 (AIF1), also known as IBA1, daintain and Protein G1, is an actin-binding protein.
Actin-binding protein that enhances membrane ruffling and RAC activation.
Enhances the actin-bundling activity of LCP1.
Binds calcium.
Plays a role in RAC signaling and in phagocytosis.
May play a role in macrophage activation and function.
Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes.
Enhances lymphocyte migration.
Plays a role in vascular inflammation